LO-3-63
LO-3-63 is a Ribociclib analogue featuring a truncated fumaramide group and acts as a CDK4/6 degrader with PROTAC properties. It degrades CDK4/6 in cells via a CUL4DCAF16-dependent pathway.
Product Specifications
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Protein Biochemistry
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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