GlcNAc-MurNAc
GlcNAc-MurNAc is a disaccharide and mild TLR4 agonist with a Kd of 383 μM for mouse TLR4. It directly binds to TLR4, activating the downstream NF-κB and IRF pathways. Additionally, GlcNAc-MurNAc ameliorates dextran sulfate sodium salt (DSS) -induced colitis in mice through a TLR4-dependent mechanism, making it useful for inflammatory bowel disease research.
Product Specifications
CAS Number
4500-70-3
Field of Research
Cell Biology, Immunology & Inflammation, Protein Biochemistry, Signal Transduction
Smiles
O ([C@H]1[C@H] (O[C@@H] (C (O) =O) C) [C@@H] (NC (C) =O) [C@H] (O) O[C@@H]1CO) [C@H]2[C@H] (NC (C) =O) [C@@H] (O) [C@H] (O) [C@@H] (CO) O2
Molecular Formula
C19H32N2O13
Molecular Weight
496.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6363272-01 0.2 mL
WDR43, CT (WDR43, KIAA0007, WD repeat-containing protein 43) (FITC)
Sign In for Pricing
View Details MBS6363272-02 5x 0.2 mL
WDR43, CT (WDR43, KIAA0007, WD repeat-containing protein 43) (FITC)
Sign In for Pricing
View Details A4000-26-AP 100 µL
ATM, phosphorylated (Ser1981) (Ataxia Telangiectasia Mutated, ATA, AT Complementation Group A, ATC, ATD, ATE) (AP) discontinued
Sign In for Pricing
View Details 