DHC-286
DHC-286 is a molecular glue degrader that targets GSPT1. It recruits GSPT1 to the CRL4CRBN ubiquitin ligase complex, facilitating its ubiquitination and subsequent degradation via the proteasome, which induces cytotoxic effects. DHC-286 holds potential for cancer research.
Product Specifications
CAS Number
2920443-08-7
Field of Research
Pharmacology & Drug Discovery
Smiles
O=C (NCC=1C=CC=CC1C (F) (F) F) COC2=CC=C3C (=O) N (CC3=C2) C4C (=O) NC (=O) CC4
Molecular Formula
C23H20F3N3O5
Molecular Weight
475.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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