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DHC-286

DHC-286 is a molecular glue degrader that targets GSPT1. It recruits GSPT1 to the CRL4CRBN ubiquitin ligase complex, facilitating its ubiquitination and subsequent degradation via the proteasome, which induces cytotoxic effects. DHC-286 holds potential for cancer research.

Product Specifications

CAS Number

2920443-08-7

Field of Research

Pharmacology & Drug Discovery

Smiles

O=C (NCC=1C=CC=CC1C (F) (F) F) COC2=CC=C3C (=O) N (CC3=C2) C4C (=O) NC (=O) CC4

Molecular Formula

C23H20F3N3O5

Molecular Weight

475.42

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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