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KPC-2-IN-3

KPC-2-IN-3 (Compound 3b) is a KPC-2 inhibitor with an IC50 of 0.533 μM and a Ki of 0.194 μM. It works synergistically with Meropenem to exhibit antibacterial activity against carbapenem-resistant K. pneumoniae K47-25, reducing bacterial count and demonstrating a post-antibiotic effect. Additionally, KPC-2-IN-3 significantly decreases lung bacterial load in a mouse pneumonia model.

Product Specifications

Field of Research

Infectious Disease & Virology

Storage Conditions

-20°C

Notes

For research use only.

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