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SK2187

SK2187 is a selective degrader of AURKAPROTAC with a DC50 of approximately 10 nM. It exhibits growth-inhibitory effects on NGP cells, with an IC50 value of 101.5 nM. SK2187 is utilized in studies of MYCN-amplified neuroblastoma.

Product Specifications

CAS Number

3038446-91-9

Field of Research

Cell Biology, Epigenetics & Chromatin, Pharmacology & Drug Discovery

Smiles

C ([C@@]1 (C (NCCOCCOCCOCCNC (COC2=C3C (C (=O) N (C3=O) C4C (=O) NC (=O) CC4) =CC=C2) =O) =O) CC[C@@H] (OC5=C (F) C (Cl) =CC=C5) CC1) C=6N=C (NC7=NC=CS7) C=CC6

Molecular Formula

C45H49ClFN7O11S

Molecular Weight

950.43

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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