SK2187
SK2187 is a selective degrader of AURKAPROTAC with a DC50 of approximately 10 nM. It exhibits growth-inhibitory effects on NGP cells, with an IC50 value of 101.5 nM. SK2187 is utilized in studies of MYCN-amplified neuroblastoma.
Product Specifications
CAS Number
3038446-91-9
Field of Research
Cell Biology, Epigenetics & Chromatin, Pharmacology & Drug Discovery
Smiles
C ([C@@]1 (C (NCCOCCOCCOCCNC (COC2=C3C (C (=O) N (C3=O) C4C (=O) NC (=O) CC4) =CC=C2) =O) =O) CC[C@@H] (OC5=C (F) C (Cl) =CC=C5) CC1) C=6N=C (NC7=NC=CS7) C=CC6
Molecular Formula
C45H49ClFN7O11S
Molecular Weight
950.43
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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