ADP-ribose/PARP-IN-1
ADP-ribose/PARP-IN-1 (Compound Ex.16) is a conjugated compound composed of a disease-targeting segment, a PARP inhibitor section, a cleavable linker, and a chelating agent. It targets specific sites via its disease-targeting part, delivering the PARP inhibitor selectively to tumor cells. Under suitable conditions, the cleavable linker releases the PARP inhibitor to hinder DNA damage repair by inhibiting PARP, while the chelating agent transports a radionuclide for cytotoxic action. This compound is applicable in prostate cancer research.
Product Specifications
CAS Number
3047557-92-3
Field of Research
Epigenetics & Chromatin, Molecular Biology
Smiles
O=C1C2=C3C (=C (NC3=CC (F) =C2) C4=CC=C (CN (C (CCCCCCC (NCCCC[C@H] (C (N[C@@H] (C (NCCC (NC[C@@H]5CC[C@@H] (C (N[C@@H] (CC6=CC7=C (C=C6) C=CC=C7) C (NCCCC[C@H] (NC (N[C@@H] (CCC (O) =O) C (O) =O) =O) C (O) =O) =O) =O) CC5) =O) =O) CC (O) =O) =O) NC (CCC (C (O) =O) N8CCN (CC (O) =O) CCN (CC (O) =O) CCN (CC (O) =O) CC8) =O) =O) =O) C) C=C4) CCN1
Molecular Formula
C92H125FN16O26
Molecular Weight
1890.07
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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