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YTHu78

YTHu78 is a KDM5B PROTAC-based degrader. It induces the degradation of KDM5B through the ubiquitin-proteasome system and triggers apoptosis in MV-4-11 and MM.1S cell lines. YTHu78 demonstrates significant antiproliferative activity against various hematologic tumor cell lines and is useful for studying hematological malignancies.

Product Specifications

Field of Research

Cell Biology, Epigenetics & Chromatin, Molecular Biology, Pharmacology & Drug Discovery, Protein Biochemistry

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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