What is the catalog number for Astringin?

The catalog number for Astringin is HY-N4093.

What sizes are available for Astringin?

Astringin is available in the following size(s): 1 mg, 5 mg, 10 mM - 1 mL, 10 mg.

How many pack sizes does Astringin come in?

Astringin is available in 4 different pack sizes.

Is Astringin in stock?

Astringin is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Astringin?

Astringin is manufactured by QuantiMol.

What is the estimated delivery time for Astringin?

Estimated delivery time for Astringin is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Astringin?

The safety data sheet for Astringin is available here: http://file.medchemexpress.com/batch_PDF/HY-N4093/Astringin-SDS-MedChemExpress.pdf.

Astringin

Astringin (trans-Astringin) is an orally active natural flavonoid compound. Astringin can inhibit the production of oxidative stress, inflammatory factors, etc. Astringin has multiple activities such as anti-oxidation, anti-inflammation, and anti-apoptosis. Astringin is also an inhibitor of ferroptosis. Astringin can be used in the research of diseases such as acute lung injury[1][2][3][4].

Product Specifications

CAS Number

29884-49-9

Product Name Alternative

Trans-Astringin

UNSPSC

12352005

Target

Akt; Apoptosis; Ferroptosis; Interleukin Related; MyD88; NF-κB; PI3K; Reactive Oxygen Species (ROS) ; Toll-like Receptor (TLR)

Type

Natural Products

Related Pathways

Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; PI3K/Akt/mTOR

Applications

Cancer-programmed cell death

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/astringin.html

Purity

99.54

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OC1=C(O)C=CC(/C=C/C2=CC(O)=CC(O[C@@H]3O[C@@H]([C@@H](O)[C@H](O)[C@H]3O)CO)=C2)=C1

Molecular Formula

C20H22O9

Molecular Weight

406.38

References & Citations

[1]Le TK, et al. Highly regioselective hydroxylation of polydatin, a resveratrol glucoside, for one-step synthesis of astringin, a piceatannol glucoside, by P450 BM3. Enzyme Microb Technol. 2017 Feb;97:34-42.|[2]Wang L, et al. Astringin protects LPS-induced toxicity by suppressing oxidative stress and inflammation via suppression of PI3K/AKT/NF-κB pathway for pediatric acute lung injury. Naunyn Schmiedebergs Arch Pharmacol. 2023 Oct;396 (10) :2369-2377.|[3]Chen B, et al. Comparison of Ferroptosis-Inhibitory Mechanisms between Ferrostatin-1 and Dietary Stilbenes (Piceatannol and Astringin) . Molecules. 2021 Feb 19;26 (4) :1092.|[4]Hu H, et al. Pharmacotherapeutic role of astringin against chromium induced nephrotoxicity via modulating TLR4/MyD88, HMGB1/RAGE and NF-κB pathway: A biochemical and pharmacokinetic approach. J Trace Elem Med Biol. 2025 May 2;89:127666.