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PPARγ agonist 19

PPARγ agonist19 (Compound 5e) is a PPARγ agonist with an IC50 of 11.27 μM for COX-1 and 0.05 μM for COX-2. It enhances glucose uptake in rat hemidiaphragm assays more effectively than pioglitazone. Additionally, PPARγ agonist19 reduces hyperglycemia and insulin resistance in type 2 diabetic rat models and protects against renal and lipid damage caused by metabolic dysfunction.

Product Specifications

Field of Research

Immunology & Inflammation, Metabolism Research, Molecular Biology, Neuroscience, Pharmacology & Drug Discovery

Storage Conditions

-20°C

Notes

For research use only.

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