AAK1-IN-10
AAK1-IN-10 (Compound 1-2) is an AAK1 inhibitor with significant enzymatic inhibition of AAK1 (IC50: 9.62 nM) . Its primary mechanism involves inhibiting adaptor-associated kinase 1 (AAK1) activity. AAK1-IN-10 exhibits minimal cardiotoxicity (IC50 = 13.7 μM) and can be utilized in research for diabetic neuralgia and postherpetic neuralgia.
Product Specifications
CAS Number
3083494-45-2
Field of Research
Neuroscience
Smiles
C (F) (F) C1=NC (=CC=C1OC[C@@] (C[C@@] (CO) (C) O) (C) N) C=2C=C (C (F) F) N=CC2
Molecular Formula
C19H23F4N3O3
Molecular Weight
417.40
Storage Conditions
-20°C
Notes
For research use only.
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