STING agonist-43
STINGagonist-43 (Compound 67) is a selective STING agonist with an EC50 of 20.53 μM. It selectively enhances the cGAMP-dependent STING pathway activation by modulating STING oligomerization. STINGagonist-43 demonstrates antitumor activity in a B16.F10 mouse melanoma model and can be utilized in cancer immunotherapy research.
Product Specifications
CAS Number
2882097-31-4
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery; Cell Biology
Smiles
O=C (OCC) CN1C2=CC=C (C=C2C (=O) C3=CC (OC) =C (C (=C31) C) C) C
Molecular Formula
C21H23NO4
Molecular Weight
353.41
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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