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STING agonist-43

STINGagonist-43 (Compound 67) is a selective STING agonist with an EC50 of 20.53 μM. It selectively enhances the cGAMP-dependent STING pathway activation by modulating STING oligomerization. STINGagonist-43 demonstrates antitumor activity in a B16.F10 mouse melanoma model and can be utilized in cancer immunotherapy research.

Product Specifications

CAS Number

2882097-31-4

Field of Research

Immunology & Inflammation, Pharmacology & Drug Discovery; Cell Biology

Smiles

O=C (OCC) CN1C2=CC=C (C=C2C (=O) C3=CC (OC) =C (C (=C31) C) C) C

Molecular Formula

C21H23NO4

Molecular Weight

353.41

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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