KRASG12C ligand-1
KRASG12C ligand-1 is a PROTAC target protein ligand utilized in synthesizing PROTAC YN14-H. YN14-H acts as a PROTAC degrader targeting KRASG12C, exhibiting antitumor activity.
Product Specifications
CAS Number
3053689-44-1
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
O=C1N (C=2C (C (=N1) N3[C@@H] (C) CN (C (C=C) =O) CC3) =CC (F) =C (N2) C4=C (OCC5CCNCC5) C=CC=C4F) C6=C (C (C) C) N=CC=C6C
Molecular Formula
C36H41F2N7O3
Molecular Weight
657.75
Storage Conditions
-20°C
Notes
For research use only.
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