DASK1
DASK1 is a selective CRBN-based PROTAC degrader targeting apoptosis signal-regulating kinase 1 (ASK1) . It forms a stable ternary complex with ASK1, facilitating its rapid and sustained degradation via the ubiquitin-proteasome pathway. dASK1 exhibits strong ASK1 degradation capabilities and is applicable for hepatitis research.
Product Specifications
CAS Number
3064086-31-0
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Smiles
O=C (NC1=NC (=CC=C1) C2=NN=CN2C (C) C) C3=CC (NC (=O) CCC (=O) NCCOCCNC4=CC=CC=5C (=O) N (C (=O) C45) C6C (=O) NC (=O) CC6) =C (F) C=C3F
Molecular Formula
C38H38F2N10O8
Molecular Weight
800.77
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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