CALR ligand 1
CALR ligand 1 (Compound 2a) is a calreticulin (CALR) ligand with anti-tumor activity against triple-negative breast cancer (TNBC) cells, exhibiting an IC50 of 0.1 μM. It induces intracellular calcium overload, leading to apoptosis in TNBC cells, making it a promising candidate for further research on triple-negative breast cancer.
Product Specifications
CAS Number
3055854-78-6
Field of Research
Cell Biology
Smiles
O=C (NC1=NNC2=NC=C (C=C21) C=3C=CC (=CC3) S (=O) (=O) C (C) C) CCl
Molecular Formula
C17H17ClN4O3S
Molecular Weight
392.86
Storage Conditions
-20°C
Notes
For research use only.
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