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2-5A

2-5A is a 5'-triphosphorylated (2',5') oligoadenylate. It acts as an immune messenger capable of enhancing RNase L immunity. By binding to RNase L and activating its endoribonuclease activity, 2-5A degrades viral mRNA and inhibits protein synthesis. This compound is useful in research on respiratory syncytial virus (RSV) and cancer.

Product Specifications

CAS Number

65954-93-0

Field of Research

Cell Biology, Infectious Disease & Virology, Molecular Biology

Smiles

O (P (OC[C@H]1O[C@H] ([C@H] (OP (OC[C@H]2O[C@H] ([C@H] (O) [C@@H]2O) N3C=4C (N=C3) =C (N) N=CN4) (=O) O) [C@@H]1O) N5C=6C (N=C5) =C (N) N=CN6) (=O) O) [C@H]7[C@@H] (O[C@H] (COP (OP (OP (=O) (O) O) (=O) O) (=O) O) [C@H]7O) N8C=9C (N=C8) =C (N) N=CN9

Molecular Formula

C30H40N15O25P5

Molecular Weight

1165.59

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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