PARP1-IN-40
PARP1-IN-40 is a highly selective and orally active PARP1 inhibitor with an IC50 of 0.19 nM for PARP1 and 26 nM for PARP2. By inhibiting PARP1, it induces DNA damage accumulation, effectively killing tumor cells. It demonstrates significant antitumor activity against BRCA-mutated MDA-MB-436 cells. Additionally, PARP1-IN-40 can be used in combination with chemotherapy for related cancer research.
Product Specifications
Field of Research
Cell Biology, Epigenetics & Chromatin, Molecular Biology
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
Z01LS-1122-LS128 5 Plates
Human SGK2 Matched Antibody Pair Set [IV11692/Poly]
Sign In for Pricing
View Details 
1341-AAT 2 Labelings
Buccutite™ Rapid PE-Cy5.5 Tandem Antibody Labeling Kit *Microscale Optimized for Labeling 25 ug Antibody Per Reaction*
Sign In for Pricing
View Details 
MBS2168437-01 0.1 mL
HRP-Linked Monoclonal Antibody to Nexilin (NEXN)
Sign In for Pricing
View Details