HSD17B13-IN-104
HSD17B13-IN-104 (Compound 32) is an orally active and potent inhibitor of HSD17B13 with high selectivity (IC50=2.5 nM) . It modulates liver lipid metabolism by inhibiting the SREBP-1c/FAS pathway and blocks the enzymatic activity of HSD17B13 to alleviate hepatic lipid accumulation. HSD17B13-IN-104 shows potential for research in metabolic dysfunction-associated fatty liver disease.
Product Specifications
CAS Number
3075100-76-1
Field of Research
Metabolism Research
Smiles
O=C (C=1SC (=NC1C) C=2C=C (F) C (F) =C (O) C2F) N (CC3=CC=C (Cl) C=C3) C (C) C
Molecular Formula
C21H18ClF3N2O2S
Molecular Weight
454.89
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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