GT-02216
GT-02216 is capable of binding allosterically to GCase, thereby enhancing its function. In primary human fibroblasts, it increases GCase activity and decreases Tau accumulation in mutant GBA1 fibroblasts. Additionally, GT-02216 offers protection to hippocampal primary neurons exposed to Tau oligomer in a rat model.
Product Specifications
CAS Number
2648407-76-3
Field of Research
Metabolism Research
Smiles
O=C (C1=NC (N) =CC (=C1) NC=2C=CC=CC2O) N3CCN (C=4C=CC=CC4) CC3
Molecular Formula
C22H23N5O2
Molecular Weight
389.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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