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DF-006

DF-006 is an innovative orally active agonist of ALPK1 (α-kinase 1) . It stimulates the innate immune response in the liver by activating the NF-κB pathway. DF-006 effectively reduces serum levels of hepatitis B virus (HBV) DNA (EC50 = 2.7 pM), HBsAg, and HBeAg, demonstrating potent antiviral activity, making it suitable for immunotherapy research in chronic hepatitis B (CHB) .

Product Specifications

CAS Number

2311947-41-6

Field of Research

Infectious Disease & Virology

Smiles

O[C@H]1[C@H] (N2C=3C (N=C2) =C (N) N=CN3) O[C@H] (COP (OP (O[C@H]4[C@@H] (OC (C) =O) [C@@H] (OC (C) =O) [C@H] (OC (C) =O) [C@@] ([C@H] (COC (C) =O) F) (O4) [H]) (=O) O) (=O) S) [C@H]1O

Molecular Formula

C25H34FN5O18P2S

Molecular Weight

805.57

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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