Topoisomerase inhibitor 6
Topoisomerase inhibitor6 (Compound REDX05931) is a dual irreversible inhibitor of DNA gyrase and topoisomerase IV, with an MIC of 0.06 μg/mL against fluoroquinolone-resistant S. aureus. It halts the DNA strand breaking-rejoining process, causing lethal DNA damage, and holds potential for studying infections caused by Gram-positive bacteria such as S. aureus and S. pneumoniae.
Product Specifications
CAS Number
2987726-03-2
Field of Research
Infectious Disease & Virology, Molecular Biology, Pharmacology & Drug Discovery
Smiles
ClC1=C2C (C3=C (C (=O) N2C4CC4) N=C (C) O3) =CC (F) =C1N5C[C@] ([C@H] (C) N) (CC5) [H]
Molecular Formula
C20H22ClFN4O2
Molecular Weight
404.87
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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