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AF151

AF151 is a METTL3 PROTAC degrader with a DC50 of 0.43 μM in MOLM-13 cells. It inhibits cell growth by significantly degrading METTL3 protein and reducing m6A levels. AF151 induces apoptosis and decreases Bcl-2 protein levels. This compound is applicable in research related to cancers such as acute myeloid leukemia (AML) .

Product Specifications

Field of Research

Cell Biology, Pharmacology & Drug Discovery

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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