SB-583355
SB-583355 (Compound 56) is a potent G2A antagonist. It is synthesized through a Suzuki reaction of 4-methoxyphenylboronic acid with 3-bromo-4-hydroxybenzoic acid under specific conditions, followed by amide coupling. SB-583355 effectively blocks G2A activation mediated by 9-HOPE or T-10148 in CHO-K1 cells expressing human G2A. This compound is useful for investigating inflammation, myeloid leukemia, and neuropathic pain.
Product Specifications
CAS Number
3040121-49-8
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Smiles
OC=1C (=CC (C (N[C@@H] (CC2=CC=CC=C2) C (NC3CCCCC3) =O) =O) =CC1) C4=CC=C (OC) C=C4
Molecular Formula
C29H32N2O4
Molecular Weight
472.58
Storage Conditions
-20°C
Notes
For research use only.
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