TFCA
TFCA is a liver X receptor α (LXRα) antagonist. It inhibits the coactivation of ligand-activated LXRα and suppresses the transcriptional expression of downstream target genes involved in fatty acid synthesis. By selectively inhibiting LXRα in the liver, TFCA reduces ligand-induced lipogenesis and fatty liver.
Product Specifications
CAS Number
895700-18-2
Field of Research
Metabolism Research
Smiles
O=C (C=CC1=CC=C (OC) C (OC) =C1) NC2=CC=C (C=C2) C (F) (F) F
Molecular Formula
C18H16F3NO3
Molecular Weight
351.32
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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