WRN inhibitor 19
WRN inhibitor 19 (Compound 40) is a WRN helicase inhibitor with an IC50 of 3.7 nM. It exhibits selective antiproliferative activity in WRN-dependent cancer cells by competitively binding to the ATP site to inhibit WRN helicase function, inducing DNA damage and causing cell cycle arrest. WRN inhibitor 19 is applicable for research in WRN-dependent cancers.
Product Specifications
Field of Research
Cell Biology, Epigenetics & Chromatin; Pharmacology & Drug Discovery, Molecular Biology
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC402911-100 1x 100 µL
Nestin (Cancer Stem Cell Marker) (NES/2911), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC401424-500 1x 500 µL
Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker) (CALD1/1424R), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC040445-500 1x 500 µL
Muscle Specific Actin (HHF35), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details