GSK2220691
SK2220691 is a potent TRPV4 inhibitor. It effectively suppresses pulmonary edema induced by GSK1016790. Additionally, SK2220691 inhibits the increase of crucial factors such as VEGF, keratinocyte-derived chemokine (KC; CXCL1), and granulocyte colony-stimulating factor (GCSF) induced by hydrochloric acid.
Product Specifications
CAS Number
1206619-37-5
Field of Research
Pharmacology & Drug Discovery
Smiles
C ([C@@H] (NC (=O) C1=CC=2C (N1) =CC=CC2) [C@@] (C) (C) C) (=O) N3[C@@]4 (CN (C (=O) C5=CC=C (C=N5) C6=CC=CC=C6) [C@@] (C4) (C3) [H]) [H]
Molecular Formula
C32H33N5O3
Molecular Weight
535.64
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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