INNO-220
INNO-220 is a molecular glue degrader targeting CK1α, exhibiting oral activity and CRBN dependency, capable of inducing cell cycle arrest at G0/G1 phase and apoptosis. INNO-220 disrupts the assembly and function of the CARD11/BCL10/MALT1 complex, inhibits the NF-κB signaling pathway, and activates the p53 pathway, making it suitable for lymphoma research.
Product Specifications
CAS Number
3032576-92-1
Field of Research
Cell Biology, Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.95% (May vary between batches)
Smiles
O=C1NC (=O) C (N2C (=O) C3=CC=C (C=C3C2) C=4C=NN (C4C=5C=CC=CC5) C) CC1
Molecular Formula
C23H20N4O3
Molecular Weight
400.43
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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