Osimertinib dimer
Osimertinibdimer is the dimer of Osimertinib. Osimertinib (AZD9291) is a covalent, orally active, irreversible, and mutation-selective EGFR inhibitor, effectively suppressing L858R (IC50=12 nM) and L858R/T790M (IC50=1 nM) EGFR. It addresses resistance to EGFR inhibitors mediated by the T790M mutation in lung cancer.
Product Specifications
CAS Number
2564638-97-5
Field of Research
Pharmacology & Drug Discovery
Smiles
O=C (C=C) NC1=CC (NC=2N=CC=C (N2) C3=CN (C=4C=CC=CC34) C) =C (OC) C=C1N (C) CC[N+] (C) (C) CCC (=O) NC5=CC (NC=6N=CC=C (N6) C7=CN (C=8C=CC=CC78) C) =C (OC) C=C5N (C) CCN (C) C
Molecular Formula
C56H67N14O4
Molecular Weight
1000.22
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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