PARP1-IN-39
PARP1-IN-39 is an inhibitor of PARP1, with an IC50 value of 0.22 nM. In human breast cancer cells, its IC50 is 1.57 nM. PARP1-IN-39 is applicable for studying cancers associated with DNA repair deficiencies, such as breast, ovarian, pancreatic, and prostate cancers, particularly those with BRCA1/2 mutations.
Product Specifications
CAS Number
3054988-47-2
Field of Research
Cell Biology, Epigenetics & Chromatin, Molecular Biology
Smiles
O=C (NCC) C1=NC (F) =C (C=C1) N2N=C3C (=C2) CN (C3) CC4=CC=C5C (NC (=O) C6=C (F) C=NN56) =C4F
Molecular Formula
C24H19F3N8O2
Molecular Weight
508.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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