Erufosine
Erufosine is an inhibitor of the PI3K/Akt and Ras/Raf/MAPK signaling pathways. It suppresses the activity of breast cancer cell lines MCF-7 and MDA-MB 231 with an IC50 of 40.95/40.8 μM, respectively. Erufosine reduces phosphorylation of PI3K (p85), Akt (PKB), and cRaf, making it applicable in research on breast cancer and myeloid leukemia.
Product Specifications
CAS Number
202867-33-2
Field of Research
Signal Transduction
Smiles
P (OCCCCCCCCCCCC/C=C\CCCCCCCC) (OCCC[N+] (C) (C) C) (=O) [O-]
Molecular Formula
C28H58NO4P
Molecular Weight
503.74
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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