DGK-IN-9
DGK-IN-9 (Compound 15) is an orally active and selective inhibitor of DGKζ with an IC50 of 6.1 nM. It is capable of activating IL-2 expression in Jurkat-IL2 nanoluc cells with an EC50 of 153 nM. DGK-IN-9 is applicable in tumor research.
Product Specifications
CAS Number
3081525-23-4
Field of Research
Immunology & Inflammation
Smiles
O=C (NC1=CC=C (OC=2C=CC=CC2F) C (=C1N (C) CCNC) C (F) (F) F) C3=NC (=CS3) C=4C=NN=CC4
Molecular Formula
C25H22F4N6O2S
Molecular Weight
546.54
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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