AMPA-IN-2

AMPA-IN-2 is an orally effective AMPA inhibitor capable of crossing the blood-brain barrier. By suppressing intrinsic neuronal excitability and inhibiting glutamatergic transmission excitability, AMPA-IN-2 alleviates seizures. In the pentylenetetrazol (PTZ) model, it demonstrates anticonvulsant effects, positioning it as a promising candidate with high broad-spectrum antiepileptic potential.