CBP/p300-IN-22
CBP/p300-IN-22 is a selective inhibitor of the CBP/EP300 bromodomain, with an IC50 of 4 nM. It exhibits high selectivity for BRD4 (1) and reduces cytokine expression induced by TNF-α as well as subsequent immune cell recruitment by inhibiting NF-κB signaling, demonstrating anticancer properties. This compound is applicable for research into rheumatoid arthritis (RA) and other TNF-α-mediated inflammatory diseases.
Product Specifications
Field of Research
Epigenetics & Chromatin, Signal Transduction
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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