Deglycobleomycin
Deglycobleomycin is an RNA cleaving agent that targets r (CUG) repeat sequences. By binding with small molecules that recognize r (CUG) exp, Deglycobleomycin can selectively cleave r (CUG) exp. Its efficiency in cleaving DNA is considerably lower than that of Bleomycin A5 (Pingyangmycin), but it exhibits enhanced selectivity for r (CUG) exp. Deglycobleomycin is useful for research on diseases associated with r (CUG) repeat expansions, such as myotonic dystrophy type 1, and the development of drugs aimed at precise targeting and cleavage of pathogenic RNA.
Product Specifications
CAS Number
78314-57-5
Field of Research
Cell Biology, Molecular Biology
Smiles
[C@H] (NC[C@@H] (C (N) =O) N) (CC (N) =O) C=1N=C (C (N[C@@H] ([C@@H] (O) C2=CN=CN2) C (N[C@@H] ([C@H] ([C@@H] (C (N[C@H] (C (NCCC3=NC (=CS3) C4=NC (C (NCCCCNC (=N) N) =O) =CS4) =O) [C@@H] (C) O) =O) C) O) C) =O) =O) C (C) =C (N) N1
Molecular Formula
C42H63N19O10S2
Molecular Weight
1058.20
Storage Conditions
-20°C
Notes
For research use only.
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