LSD1-IN-43
LSD1-IN-43 is a highly selective, reversible, and orally active LSD1 inhibitor with blood-brain barrier permeability, showing an IC50 value of 0.8 μM. It exhibits lower inhibitory activity against LSD1 homologs MAO-A and MAO-B. LSD1-IN-43 significantly inhibits Aβ aggregation and enhances neuronal cell viability induced by Aβ. It is applicable in Alzheimer's disease (AD) research.
Product Specifications
Field of Research
Epigenetics & Chromatin, Metabolism Research, Neuroscience
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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