Transthyretin-IN-4
Transthyretin-IN-4 (Compound B26) is a bivalent inhibitor of transthyretin (TTR) amyloidosis, with a bIC50 of 0.09 μM and a pIC50 of 1.4 μM. It is applicable for research in heart failure with preserved ejection fraction (HFpEF) and life-threatening arrhythmias.
Product Specifications
CAS Number
2765296-93-1
Smiles
O=C (O) C=1C=CN=CC1NC2=CC (Cl) =C (OCCOCCCOC3=C (Cl) C=C (C=C3Cl) CCC (=O) O) C (Cl) =C2
Molecular Formula
C26H24Cl4N2O7
Molecular Weight
618.29
Storage Conditions
-20°C
Notes
For research use only.
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