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Transthyretin-IN-4

Transthyretin-IN-4 (Compound B26) is a bivalent inhibitor of transthyretin (TTR) amyloidosis, with a bIC50 of 0.09 μM and a pIC50 of 1.4 μM. It is applicable for research in heart failure with preserved ejection fraction (HFpEF) and life-threatening arrhythmias.

Product Specifications

CAS Number

2765296-93-1

Smiles

O=C (O) C=1C=CN=CC1NC2=CC (Cl) =C (OCCOCCCOC3=C (Cl) C=C (C=C3Cl) CCC (=O) O) C (Cl) =C2

Molecular Formula

C26H24Cl4N2O7

Molecular Weight

618.29

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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