ZLD115
ZLD115 (compound 44) is a FB23-derivated inhibitor of Fat Mass and Obesity-associated Protein (FTO) . ZLD115 is an antileukemic agent, exhibiting antiproliferative activity against leukemic cell lines[1].
Product Specifications
CAS Number
2980653-93-6
UNSPSC
12352005
Target
Fat Mass and Obesity-associated Protein (FTO)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/zld115.html
Purity
99.87
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=C(C=CC=C1NC2=C(C=C(C=C2C3CC3)C4=C(ON=C4C)C)Cl)CN5CCCOCC5)O
Molecular Formula
C27H30ClN3O4
Molecular Weight
496.00
References & Citations
[1]Xiao P, et al. Rational Design of RNA Demethylase FTO Inhibitors with Enhanced Antileukemia Drug-Like Properties. J Med Chem. 2023 Jul 7.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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