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Ligritinib

Ligritinib (AB801) is an orally active inhibitor of the AXL receptor tyrosine kinase. By inhibiting the kinase activity of AXL, Ligritinib blocks its downstream signaling pathways. It is utilized in cancer research, particularly in studies involving non-small cell lung cancer (NSCLC) in combination with chemotherapy.

Product Specifications

CAS Number

3024588-48-2

Field of Research

Signal Transduction

Smiles

CC1=C (C2=CC=C (C=3C4=CC (C=5C=C6CC[C@@H] (N7C8CC7COC8) CCC6=CC5) =CN=C4NN3) N=C2) N=CC=C1

Molecular Formula

C33H32N6O

Molecular Weight

528.65

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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