VU0514009
VU0514009 is a competitive antagonist of chemokine-like receptor 1 (CMKLR1) with an EC50 of 2 nM. It effectively inhibits chemerin-9-induced arrestin recruitment and receptor internalization, significantly reducing Ca2+ flux responses in HEK293 cells. This compound shows potential for research in inflammatory diseases and metabolic syndrome.
Product Specifications
CAS Number
932973-77-8
Field of Research
Pharmacology & Drug Discovery
Smiles
O=C1NC (=NC=C1S (=O) (=O) C2=CC=C (C (Cl) =C2) C) SCC (=O) NC3=CC (=CC=C3OC) C
Molecular Formula
C21H20ClN3O5S2
Molecular Weight
493.98
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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