SB-T-1214
SB-T-1214 (SBT) is a taxane-based drug known for its ability to effectively suppress the expression of stem cell-related genes (Oct4, Sox2, and c-Myc) and induce apoptosis in drug-resistant tumorigenic CD133+/CD44+ colon cancer spheroids. In Pgp+ DLD-1 human colon tumor xenograft mouse models, SB-T-1214 successfully inhibits tumor growth. This compound is relevant for anti-tumor research, particularly against drug-resistant tumors such as colon, pancreatic, and renal cancers.
Product Specifications
CAS Number
178250-23-2
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Smiles
O (C (C) =O) [C@]12[C@]3 ([C@H] (OC (=O) C4=CC=CC=C4) [C@@]5 (O) C (C) (C) C ([C@@H] (OC (=O) C6CC6) C (=O) [C@]3 (C) [C@@H] (O) C[C@]1 (OC2) [H]) =C (C) [C@@H] (OC ([C@@H] ([C@@H] (NC (OC (C) (C) C) =O) C=C (C) C) O) =O) C5) [H]
Molecular Formula
C45H59NO15
Molecular Weight
853.95
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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