AZ12943203
AZ12943203 (Compound 13e) is a PET radioligand targeting GSK-3, with a Kd of 2.94 nM. It demonstrates significant inhibitory potency against GSK-3β (IC50: 4.44 nM) and specifically binds to GSK-3-rich regions in the rodent brain. AZ12943203 is applicable for imaging neurodegenerative diseases, particularly Alzheimer's disease.
Product Specifications
Field of Research
Signal Transduction, Stem Cell & Developmental Biology
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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