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DDD2

DDD2 is a selective and efficient VHL-mediated PROTAC degrader specifically targeting NUDT5. It effectively induces substantial degradation of NUDT5. DDD2 consists of the warhead TH10184 and the VHL-recruiting ligand VH032, connected via a saturated aliphatic eight-carbon linker. DDD2 is applicable in cancer research, including studies on lymphocytic leukemia and osteosarcoma.

Product Specifications

Field of Research

Pharmacology & Drug Discovery, Signal Transduction

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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