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KRAS IN-44

KRAS IN-44 (Compound S2C2M2) is a PDE6D degrader. It inhibits PDE6D-dependent KRAS transport and downstream signaling pathways. Additionally, KRAS IN-44 downregulates EGF-induced phosphorylation of PI3K, AKT, and mTOR. It promotes apoptosis and exhibits antitumor activity against hepatoblastoma.

Product Specifications

Field of Research

Cell Biology, Metabolism Research, Signal Transduction

Storage Conditions

-20°C

Notes

For research use only.

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