KRAS IN-44
KRAS IN-44 (Compound S2C2M2) is a PDE6D degrader. It inhibits PDE6D-dependent KRAS transport and downstream signaling pathways. Additionally, KRAS IN-44 downregulates EGF-induced phosphorylation of PI3K, AKT, and mTOR. It promotes apoptosis and exhibits antitumor activity against hepatoblastoma.
Product Specifications
Field of Research
Cell Biology, Metabolism Research, Signal Transduction
Storage Conditions
-20°C
Notes
For research use only.
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