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NLRP3-IN-79

NLRP3-IN-79 (Compound B6) is a selective inhibitor of the NLRP3 inflammasome with an IC50 value of 10.69 nM. It blocks the assembly of the NLRP3 inflammasome by disrupting the interaction between NEK7 and NLRP3. NLRP3-IN-79 shows potential for research in NLRP3-driven inflammatory diseases such as systemic inflammation, peritonitis, and colitis.

Product Specifications

Field of Research

Cell Biology, Immunology & Inflammation, Signal Transduction

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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