FLT3-IN-33
FLT3-IN-33 (Compound 7r) is a potent FLT3 inhibitor with an IC50 of 7.82 nM. It exhibits excellent anticancer activity against acute myeloid leukemia (AML) cells, such as MV4-11 and MOLM-13 cells. FLT3-IN-33 significantly induces apoptosis and inhibits the phosphorylation of the FLT3 pathway, making it useful for research in AML and other cancers.
Product Specifications
CAS Number
3035801-67-0
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
N (C=1C (=CN=C (NCCC) N1) C=2NC=3C (N2) =CC=C (C3) N4CCN (C) CC4) [C@@H]5CC[C@@H] (O) CC5
Molecular Formula
C25H36N8O
Molecular Weight
464.61
Storage Conditions
-20°C
Notes
For research use only.
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