SARS-CoV-2-IN-115
SARS-CoV-2-IN-115 (Compound 3e) is a potent inhibitor of SARS-CoV-2, showing strong antiviral activity in infected Calu-3 cells with an EC50 of 1.7 μM. It effectively inhibits human dihydroorotate dehydrogenase (HsDHODH) activity with an IC50 of 1.5 μM. Importantly, SARS-CoV-2-IN-115 maintains immune response without affecting the proliferation of CD4 T cells.
Product Specifications
CAS Number
2557232-80-9
Field of Research
Cell Biology, Infectious Disease & Virology, Metabolism Research, Molecular Biology
Smiles
O=C (NC1=CC=C (C#CC2=CC=CC (N) =C2) C=C1) C
Molecular Formula
C16H14N2O
Molecular Weight
250.30
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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