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SARS-CoV-2-IN-115

SARS-CoV-2-IN-115 (Compound 3e) is a potent inhibitor of SARS-CoV-2, showing strong antiviral activity in infected Calu-3 cells with an EC50 of 1.7 μM. It effectively inhibits human dihydroorotate dehydrogenase (HsDHODH) activity with an IC50 of 1.5 μM. Importantly, SARS-CoV-2-IN-115 maintains immune response without affecting the proliferation of CD4 T cells.

Product Specifications

CAS Number

2557232-80-9

Field of Research

Cell Biology, Infectious Disease & Virology, Metabolism Research, Molecular Biology

Smiles

O=C (NC1=CC=C (C#CC2=CC=CC (N) =C2) C=C1) C

Molecular Formula

C16H14N2O

Molecular Weight

250.30

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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